Thus, unless individually defined (multi-)genetic therapy suddenly becomes technically and economically viable, we need to ask how much value there is in simply cataloguing yet more mutations. Maybe we should thus take a moment to reflect on the shortcomings of the previous 40 years, to avoid repeating the same errors and to prevent our efforts from being futile again.įor example, recent progress on the sequencing of cancer genomes ( Stratton et al, 2009) reinforces the concept that all cancers are genetically individual ( Greenman et al, 2007). However, as you point out, despite the voluminous amount of published knowledge, we are still waiting for substantial progress in actual therapy. In your recent editorial about the 40th anniversary of Nixon's war on cancer ( Jacobs, 2011) you correctly argue for continuing the effort and funding to defeat cancer.
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